医療言語処理ことはじめ〜ことばのAIで何ができる?〜

Transcript

1. ౦େපӃ์ࣹઢՊϨδσϯτηϛφʔ ҩྍݴޠॲཧ͜ͱ͸͡Ί ʙ͜ͱ͹ͷ"*ͰԿ͕Ͱ͖Δʁʙ 
   
    ౦ژେֶେֶӃҩֶܥݚڀՊ ੜମ෺ཧҩֶઐ߈ % தଜ ༏ଠ
2. தଜ ༏ଠ :VUB
   /BLBNVSB     ʙ  ʙ ࣗݾ঺հ ๺ւಓࡳຈࢢ ੜ·Ε ๺ྮߴ౳ֶߍ ଔۀ ౦ژେֶҩֶ෦ҩֶՊ ଔۀ ์ࣹઢՊઐ໳ҩ औಘ ౦େපӃ์ࣹઢՊ ΠϝʔδϥϘ *$"-
   େֶӃੜ ݚڀςʔϚ
   ࣗવݴޠॲཧͷը૾਍அ΁ͷԠ༻ ಸྑઌ୺Պֶٕज़େֶӃେֶ /"*45 ιʔγϟϧɾίϯϐϡʔςΟϯάݚڀࣨ ࠃ಺ཹֶ /-1एखͷձγϯϙδ΢Ϝ ӡӦҕһ
3. ҩྍݴޠॲཧͱ͸ʁ ҩྍݴޠॲཧ #JPNFEJDBM
   OBUVSBM
   MBOHVBHF
   QSPDFTTJOH • ࣗવݴޠॲཧΛҩྍʹԠ༻͢Δ͜ͱ ࣗવݴޠॲཧ /BUVSBM
   MBOHVBHF
   QSPDFTTJOH
   /-1 • ࣗવݴޠΛίϯϐϡʔλͰॲཧ͢Δ͜ͱ ͜ͱ͹ͷ"* ࣗવݴޠ /BUVSBM
   MBOHVBHF • ਓ͕ؒҙࢥૄ௨ʹ࢖͏ࣗવൃੜతͳݴޠ ೔ຊޠ
   ӳޠ
   ʜ ਓ޻ݴޠ "SUJGJDJBM
   MBOHVBHF • ਓҝతʹ࡞ΒΕͨݴޠ Τεϖϥϯτ
   ίϯϐϡʔλݴޠ
   ʜ ٕज़తʹ͸ ΄΅ಉ͡
4. ͖͔͚ͬ ͳͥ์ࣹઢՊҩͳͷʹݴޠΛʁ ˡ ిࢠΧϧς΍ಡӨϨϙʔτͰͷݕࡧ͠ʹ͕͖͔͚ͬ͘͞ $07*% ✅ $07*%ͱͯ͠యܕత ❌ $07*%͸൱ఆత ؊ࡉ๔؞ ✅ 4
   4ଟൃ؊ࡉ๔؞͍ٙ ❌ ؊ࡉ๔؞ज़ޙɿ࠶ൃΛೝΊ·ͤΜ ❌ ଟൃ)$$ज़લ ˡ ِཅੑ $07*%Ͱ͸ͳ͍ ˡ ِӄੑ ݺশΏΕ͕͋Δͱर͑ͳ͍ ˡ ِཅੑ ͢Ͱʹ࣏ྍޙ ݕࡧػೳɼͲͷ͘Β͍࢖͍ͬͯ·͔͢ʁ ʢ͋·Γຖ೔͘͢͝པ͍ͬͯΔํ͸͍ͳ͍ͷͰ͸ʣ
5. ͓͠ͳ͕͖ 01 ͜ͱ͹ͷ"*͸Ͳ͜·ͰਐԽ͔ͨ͠ 02 ͜ͱ͹ͷ"*͸Ͳ͜·Ͱҩྍʹߩݙ͍ͯ͠Δ͔ 03 ͜ͱ͹ͷ"*Λ΋ͬͱҩྍʹ׆͔ͨ͢Ίʹ͸
6. ͜ͱ͹ͷ"*͸Ͳ͜·ͰਐԽ͔ͨ͠
7. ͜ͱ͹ͷ"*͸Ͳ͜·ͰਐԽ͔ͨ͠ 2017 BERT J Devlin et al. Google LLC. 2014 word2vec T Mikolov et al. Google LLC. 2017 Transformer A Vaswani et al. Google Brain 2019 T5 C Raffel et al. Google LLC. 1990's〜 େྔσʔλ ͔Βͷֶश ʙ1980's ਓ͕ؒஞҰ ϧʔϧΛ ॻ͖Լ͢ 2016 ౦ϩϘ͘Μ ϓϩδΣΫτ ऴྃ 2018 GPT A Radford et al. Open AI 2021 DALL-E A Ramesh et al. Open AI ɾౙͷ࣌୅͸աڈͷ΋ͷ
8. 2017 BERT J Devlin et al. Google LLC. 2014 word2vec T Mikolov et al. Google LLC. 2017 Transformer A Vaswani et al. Google Brain 2019 T5 C Raffel et al. Google LLC. 1990's〜 େྔσʔλ ͔Βͷֶश ʙ1980's ਓ͕ؒஞҰ ϧʔϧΛ ॻ͖Լ͢ 2016 ౦ϩϘ͘Μ ϓϩδΣΫτ ऴྃ 2018 GPT A Radford et al. Open AI 2021 DALL-E A Ramesh et al. Open AI ɾౙͷ࣌୅͸աڈͷ΋ͷ IUUQTEJBNPOEKQBSUJDMFT ͜ͱ͹ͷ"*͸Ͳ͜·ͰਐԽ͔ͨ͠
9. 2017 BERT J Devlin et al. Google LLC. 2014 word2vec T Mikolov et al. Google LLC. 2017 Transformer A Vaswani et al. Google Brain 2019 T5 C Raffel et al. Google LLC. 1990's〜 େྔσʔλ ͔Βͷֶश ʙ1980's ਓ͕ؒஞҰ ϧʔϧΛ ॻ͖Լ͢ 2016 ౦ϩϘ͘Μ ϓϩδΣΫτ ऴྃ 2018 GPT A Radford et al. Open AI 2021 DALL-E A Ramesh et al. Open AI ɾౙͷ࣌୅͸աڈͷ΋ͷ ɾ೥͔ΒจॻಡղείΞ͸ਓؒҎ্ IUUQTEJBNPOEKQBSUJDMFT ͜ͱ͹ͷ"*͸Ͳ͜·ͰਐԽ͔ͨ͠
10. 2017 BERT J Devlin et al. Google LLC. 2014 word2vec T Mikolov et al. Google LLC. 2017 Transformer A Vaswani et al. Google Brain 2019 T5 C Raffel et al. Google LLC. 1990's〜 େྔσʔλ ͔Βͷֶश ʙ1980's ਓ͕ؒஞҰ ϧʔϧΛ ॻ͖Լ͢ 2016 ౦ϩϘ͘Μ ϓϩδΣΫτ ऴྃ 2018 GPT A Radford et al. Open AI 2021 DALL-E A Ramesh et al. Open AI ɾౙͷ࣌୅͸աڈͷ΋ͷ ɾ೥͔ΒจॻಡղείΞ͸ਓؒҎ্ ͜ͱ͹ͷ"*͸Ͳ͜·ͰਐԽ͔ͨ͠
11. 2017 BERT J Devlin et al. Google LLC. 2014 word2vec T Mikolov et al. Google LLC. 2017 Transformer A Vaswani et al. Google Brain 2019 T5 C Raffel et al. Google LLC. 1990's〜 େྔσʔλ ͔Βͷֶश ʙ1980's ਓ͕ؒஞҰ ϧʔϧΛ ॻ͖Լ͢ 2016 ౦ϩϘ͘Μ ϓϩδΣΫτ ऴྃ 2018 GPT A Radford et al. Open AI 2021 DALL-E A Ramesh et al. Open AI ɾౙͷ࣌୅͸աڈͷ΋ͷ ɾ೥͔ΒจॻಡղείΞ͸ਓؒҎ্ ͜ͱ͹ͷ"*͸Ͳ͜·ͰਐԽ͔ͨ͠
12. 2017 BERT J Devlin et al. Google LLC. 2014 word2vec T Mikolov et al. Google LLC. 2017 Transformer A Vaswani et al. Google Brain 2019 T5 C Raffel et al. Google LLC. 1990's〜 େྔσʔλ ͔Βͷֶश ʙ1980's ਓ͕ؒஞҰ ϧʔϧΛ ॻ͖Լ͢ 2016 ౦ϩϘ͘Μ ϓϩδΣΫτ ऴྃ 2018 GPT A Radford et al. Open AI 2021 DALL-E A Ramesh et al. Open AI ɾౙͷ࣌୅͸աڈͷ΋ͷ ɾ೥͔ΒจॻಡղείΞ͸ਓؒҎ্ ɾ࠷ۙͷϒϨΠΫεϧʔͷଟ͘͸(PPHMFൃ ʢେྔͷϚγϯͱେྔͷݚڀऀ͕͍Δʣ ͜ͱ͹ͷ"*͸Ͳ͜·ͰਐԽ͔ͨ͠
13. ΋͏গ͠۩ମతʹɾɾɾ ͜ͱ͹ͷ"*͸Ͳ͜·ͰਐԽ͔ͨ͠
14. ɾҰੲલ͸ɼϘτϜΞοϓͳղੳ͕ओྲྀ ᶃܗଶૉղੳ ୯ޠ෼ׂ
    ඼ࢺ൑ఆ ᶄߏจղੳ ۟ߏ଄΍܎Γड͚Λಉఆ ᶅΑΓਐΜͩλεΫ ࢦࣔޠ΍ݴ͍׵͑Λೝࣝ ڞࢀরղੳɾরԠղੳ จॻશମͷྲྀΕΛղੳ ஊ࿩ߏ଄ղੳ ԞଜֶΒ
    ࣗવݴޠॲཧγϦʔζ
    ߏจղੳ
    ίϩφࣾ IUUQTUXJUUFSDPNOBLBNVSBLJIJSPTUBUVTQIPUP ԞଜֶΒ
    ࣗવݴޠॲཧγϦʔζ
    จ຺ղੳ ड़ޠ߲ߏ଄ɾরԠɾஊ࿩ߏ଄ͷղੳ
    
    ίϩφࣾ ͜ͱ͹ͷ"*͸Ͳ͜·ͰਐԽ͔ͨ͠
15. ɾҰੲલ͸ɼϘτϜΞοϓͳղੳ͕ओྲྀ ˣ ɾਂ૚ֶशʹΑΓɼਖ਼ղσʔλ͕େྔʹ͋Ε͹ʜ ɾਓ͕ؒஞҰϧʔϧΛࢦࣔ͠ͳͯ͘΋ ɾ్தͷղੳΛඈ͹ͯ͠Ұؾʹ ໰୊Λղ͚Δ͜ͱ͕૿͑ͨ ɾͰ͖Δ͜ͱͷ෯΋޿͕͍ͬͯΔ͠ɼੑೳ΋্͕͍ͬͯΔ ͜ͱ͹ͷ"*͸Ͳ͜·ͰਐԽ͔ͨ͠
16. ײ৘෼ੳ r :PV5VCF ɾίϝϯτ͕඄ᨱதইʹ͋ͨΔ͔൱͔൑ఆ ˠ ౤ߘલʹ஫ҙשى IUUQTUFDIDSVODIDPNZPVUVCFJOUSPEVDFTOFXGFBUVSFTUPBEESFTTUPYJDDPNNFOUT IUUQTTVQQPSUHPPHMFDPNZPVUVCFUISFBEGBRIPMEQPUFOUJBMMZJOBQQSPQSJBUFDPNNFOUTGPSSFWJFX IMFO ͜ͱ͹ͷ"*͸Ͳ͜·ͰਐԽ͔ͨ͠
17. நग़ܕ࣭໰Ԡ౴ r (PPHMFݕࡧ ɾ8FCϖʔδΛબఆ ˠ ౴͑ʹ͋͏ՕॴΛநग़ ˠ ௚઀දࣔ IUUQTXXXKSTPSKQNPEVMFTDJUJ[FOJOEFYQIQ DPOUFOU@JE ͜ͱ͹ͷ"*͸Ͳ͜·ͰਐԽ͔ͨ͠
18. ػց຋༁ r %FFQ- ʙ IUUQTXXXEFFQMDPNUSBOTMBUPS ͜ͱ͹ͷ"*͸Ͳ͜·ͰਐԽ͔ͨ͠
19. ୈࡾճ ৽نӦۀઌ։୓ϓϩδΣΫτݕ౼ٞࣄ࿥ ೔ఔɿ
     ৔ॴɿຊࣾ"ձٞࣨ ࢀՃऀʢܟশུʣɿ˔˔՝௕ɺ˔˔ɺ˔˔ɺ˔˔ 
    ৽نλʔήοτީิௐࠪ಺༰ͷڞ༗ͱબఆ 
    "*ͳͲͷ৽نٕज़ʹ਌࿨ੑͷߴ͍ΞʔϦʔΞμϓλʔ૚ʢ˔˔ʣ ૝ఆ௨Γڵຯؔ৺͸ڧ࣋ͪ͘ૣ͘ࢼ͍ͨ͠ͱ͍͏੠͕ଟ͔ͬͨɻ ͨͩྲྀߦʹහײͳ෼ɺ๞͖΋ૣ͘ɺ௕ظతͳλʔήοτͱͯ͠։୓͍ͯ͘͠ͷ͸ඇৗʹ೉͍͠ɻ 
    %*/,T૚ʢ˔˔ʣ ࣗ෼ͷ࣌ؒΛ๛͔ʹ͢ΔͨΊʹׂ͚Δ͕࣌ؒଟ͘ɺ ·ͨۚમతʹ΋༨༟͕͋Δ͜ͱ͕ଟ͘ඇৗʹ૬ੑΑ͍ɻ 
    ΞΫςΟϒγχΞ૚ʢ˔˔ʣ ΞΫςΠϒγχΞ૚͸1$΍εϚϗΛ׬શʹ࢖͍͜ͳ͍ͤͯΔ૚͕ଞͷηάϝϯτΑΓগͳ͍ͨΊվ ળޮՌ͸ඇৗʹେ͖͍ɻ ͨͩಋೖʹ͔͔Δίετ΋େ͖͘ଞͰ՝୊Λચ͍ग़͔ͯ͠Βͷ΄͏͕ྑ͍ͱߟ͑Δɻ ɾௐࠪ݁ՌΛ౿·͑%*/,T૚ΛϝΠϯλʔήοτͱͯ͠ݕ౼Λ͢͢ΊΔɻ 
    ࣍ճ΁ͷ॓୊ࣄ߲ʢΞΫγϣϯϓϥϯʣ 
    %*/,T૚ϖϧιφ࡞੒ʢ˔˔ʣ %*/,T૚ͷϖϧιφ࡞੒ͷࡍʹஉঁͦΕͧΕͷଆͰͷ࡞੒͕๬·͍͠ɻ ·ͨൺֱͱ͍͏ҙຯͰ͸෉්ʹࢠڙҰਓͷύλʔϯ΋Ұͭ࡞ΔͱΑ͍ͷͰ͸ͳ͍͔ɻ 
    %*/,T૚΁ͷޮ཰తͳΞϓϩʔνͷબఆʢ˔˔ʣ %*/,T૚͸ωοτϝσΟΞͰ͸ԿΛಡΜͰ͍Δͷ͔ɻ৘ใऩू͸Ͳ͔͜Β͍ͯ͠Δͷ͔ɻීஈͷڵ ຯؔ৺͸Ͳͷ͋ͨΓʹ͋Δͷ͔ɻͳͲɻ 
    ෦௕ใࠂձʹ޲͚ͨใࠂࢿྉ࡞੒ʢ˔˔ˠ˔˔՝௕ʣ ࣍ճͷ෦௕ձͰ͸؅ঠ໾һ΋ࢀՃ༧ఆͷͨΊࠓ·ͰҎ্ʹࢿྉΛ࡞ΓࠐΉඞཁ͋Γɻ ·ͨਤΛଟ͘࢖͏ͱͱ΋ʹҰͭҰͭͷεϥΠυ͸୹͘੾Γ෼͚ͨ΋ͷ͕޷·ΕΔɻ IUUQTXXXEJHFTUFMZ[BBJ ୈࡾճɺ৽نӦۀઌ։୓ϓϩδΣΫτݕ౼ٞࣄ࿥͕೔ɺ։࠵͞ΕΔɻ ৽نλʔήοτީิௐࠪ಺༰ͷڞ༗ͱબఆɺ࣍ճ΁ͷ॓୊ࣄ߲ͷબఆɻ %*/,4૚ϖϧιφ࡞੒ɺ෦௕ใࠂձʹ޲͚ͨใࠂࢿྉ࡞੒ͳͲɻ ࣗಈཁ໿ r &-*;"
    %*(&45
    ʙ ͜ͱ͹ͷ"*͸Ͳ͜·ͰਐԽ͔ͨ͠
20. ΞϚϏΤʢྺ࢙తԾ໊ݣɿΞϚϏϭʣ͸ɺ೔ຊʹ఻ΘΔ൒ਓ൒ڕͷ༯ոɻޫً࢟͘Ͱւத͔ΒݱΕɺ๛࡞΍ӸපͳͲͷ ༧ݴΛ͢Δͱ఻͑ΒΕ͍ͯΔɻߐށ࣌୅ޙظͷංޙࠃʢݱɾ۽ຊݝʣʹݱΕͨͱ͍͏ɻ͜ͷ࿩͸ૠਤ෇͖Ͱנ൛ʹऔΓ ্͛ΒΕɺԕ͘ߐށʹ·Ͱ఻͑ΒΕͨɻ߂Խ೥݄த०ʢ೥্݄०ʣͷ͜ͱɺຖ໷ɺւதʹޫΔ෺ମ͕ग़຅ͯ͠ ͍ͨͨΊɺ໾ਓ͕ෝ͍ͨͱ͜ΖɺͦΕ͕࢟Λݱͨ͠ɻ࢟ܗʹ͍ͭͯݴ༿Ͱ͸ॻ͖ཹΊΒΕ͍ͯͳ͍͕ɺૠਤ͕ఴ͑ΒΕ ͍ͯΔɻ ͦͷऀ͸ɺ໾ਓʹରͯ͠ʮࢲ͸ւதʹॅΉΞϚϏΤͱਃ͢ऀͳΓʯͱ໊৐Γɺʮ౰೥ΑΓϲ೥ͷؒ͸ॾࠃͰ ๛࡞͕ଓ͕͘Ӹප΋ྲྀߦ͢Δɻࢲͷ࢟Λඳ͍ͨֆΛਓʑʹૣʑʹݟͤΑɻʯͱ༧ݴΊ͍ͨ͜ͱΛࠂ͛ɺւͷத΁ͱؼͬ ͯߦͬͨɻ೥୅͕ಛఆͰ͖Δ࠷ݹͷྫ͸ɺఱอ೥ʢ೥ʣͷӽޙࠃʢݱɾ৽ׁݝʣʹग़ݱͨ͠ʮւ඙ʢಡΈͷਪ ఆɿ͋·ͼ͜ʣʯΛهड़ͨ͠נ൛ʢʰ௶઒ຊʱͱ͍͏ɻ෱Ҫݝཱਤॻؗॴଂʣɺͦͷૠֆʹඳ͔Εͨւ඙͸ɺ಄͔Β͍ ͖ͳΓຊͷ଍͕ੜ͑ͨʢ಑ମͷͳ͍ʣܗঢ়ͰɺਓؒͷΑ͏ͳࣖΛ͠ɺ໨͸·Δ͘ɺޱ͕ಥग़͍ͯ͠Δɻͦͷ೥தʹ೔ຊ ਓޱͷׂͷࢮ໓Λ༧ݴ͠ɺͦͷ૾ͷֆࡳʹΑΔٹࡁΛ஧ࠂ͍ͯ͠Δɻ ΫΠζࣗಈੜ੒ r (PPHMF
    5
    ʙ ɾࢿྉͱ౴͑ʹ͋ͬͨ໰୊จΛੜ੒͢Δ IUUQTDPMBCSFTFBSDIHPPHMFDPNHJUIVCTPOPJTBEFFQRVFTUJPOHFOFSBUJPOCMPCNBJOU@KBQBOFTF@RVFTUJPO@HFOFSBUJPOJQZOC ࢿྉ ౴͑ ංޙࠃʢݱɾ۽ຊݝʣ ߐށ࣌୅ͷͲͷࠃʹ ΞϚϏΤ͕ݱΕͨͷ Ͱ͔͢ ໰୊ ຊ ʮւ඙ʯʹ͸ ଍͕͍ͭ͘ ͋Γ·͔ͨ͠ ๛࡞΍ӸපͳͲ ΞϚϏΤ͸ւத͔Β ԿΛ༧ݴ͢Δͱ ݴΘΕ͍ͯ·͔͢ ໰୊ ໰୊ ౴͑ ౴͑ ͜ͱ͹ͷ"*͸Ͳ͜·ͰਐԽ͔ͨ͠
21. ςΩετ͔Βͷը૾ੜ੒ r 0QFO"* %"--&
    ʙ IUUQTPQFOBJDPNCMPHEBMMF ͜ͱ͹ͷ"*͸Ͳ͜·ͰਐԽ͔ͨ͠
22. ର࿩γεςϜ r ΤΞϑϨϯυ ʙ IUUQTBJSGSJFOEBJKB ͜ͱ͹ͷ"*͸Ͳ͜·ͰਐԽ͔ͨ͠
23. ·ͱΊ 01 ͜ͱ͹ͷ"*͸Ͳ͜·ͰਐԽ͔ͨ͠ʁ ͢ͰʹจॻಡղείΞ͸ਓؒΛ͓͑ͯ͜Γɼ Ұ෦ͷλεΫͰ͸ਓؒͱ۠ผ͕͖ͭʹ͍͘͜ͱ΋
24. ͜ͱ͹ͷ"*͸Ͳ͜·Ͱҩྍʹߩݙ͍ͯ͠Δ͔
25. IUUQTKBQBO[EOFUDPNBSUJDMF
    ΑΓվม ͳͥɼ"*͸·ͩ໘౗ͳ࢓ࣄΛ ୣͬͯ͘Εͳ͍ͷ͔ʁ ݬ໓ظ ਓ޻஌ೳ ͦΖͦΖ໘౗ͳ࢓ࣄΛୣͬͯ͘ΕΔ͸ͣͰ͸ʜʁ ͜ͱ͹ͷ"*͸Ͳ͜·Ͱҩྍʹߩݙ͍ͯ͠Δ͔
26. ҩྍݱ৔ ɾͳ͔ͳ͔࢓ࣄ͕ࣗಈԽ͞Εͳ͍ "*ݚڀऀ Ұ෦ͷҙݟ ɾ˓˓ͷ৬ۀ͸"*ʹୣΘΕΔʂ ɾ์ࣹઢՊҩ͸ཁΒͳ͍ʂ Ϊϟοϓ IUUQTUXJUUFSDPN&SJD5PQPMTUBUVT T
    ΑΓվม ͦΖͦΖ໘౗ͳ࢓ࣄΛୣͬͯ͘ΕΔ͸ͣͰ͸ʜʁ ͜ͱ͹ͷ"*͸Ͳ͜·Ͱҩྍʹߩݙ͍ͯ͠Δ͔
27. ೥݄ݱࡏɼ '%"ঝೝ͞Εͨҩྍ"*ػثʹ ࣗવݴޠॲཧΛओػೳͱͨ͠΋ͷ͸ݟ͔ͭΒͳ͍ ˞੡඼ͷ  L
    1SFNBSLFU
    /PUJGJDBUJPO
    4VNNBSZͷจॻதʹ MBOHVBHF
    QSPDFTTJOH
    PS
    UFYU
    NJOJOH
    ΛؚΉ݅਺ 
    ݅ ˞ػೳͷҰ෦ͱͯ͠ಡӨϨϙʔτ࡞੒ࢧԉΛᨳ͍ͬͯΔ΋ͷͳͲ͸͋Δ ྫ
    .&%05IZSPJE
    .&%0
    %9
    1UF
    -UE IUUQTXXXGEBHPWNFEJDBMEFWJDFTTPGUXBSFNFEJDBMEFWJDFTBNEBSUJGJDJBMJOUFMMJHFODFBOENBDIJOFMFBSOJOHBJNMFOBCMFENFEJDBMEFWJDFT ͜ͱ͹ͷ"*͸Ͳ͜·Ͱҩྍʹߩݙ͍ͯ͠Δ͔
28. ࢒೦ͳ͕Βɼݱ৔Ͱͷ࣮༻Խ͸·ͩ ˣ ͳ͔ͥʁ ͜ͱ͹ͷ"*͸Ͳ͜·Ͱҩྍʹߩݙ͍ͯ͠Δ͔
29. ⁞ "*جૅٕज़ͷൃల "*ͷ࢓૊Έʹର͢Δཧ࿦తɾجૅతͳݚڀ   ը૾ॲཧࣗવݴޠॲཧͷൃల "*ݚڀ༻ͷඇҩྍσʔλΛ࢖ͬͨݚڀ ⁡ ҩྍݱ৔Ͱͷݕূ ҩྍݱ৔ʹ࣮ࡍʹߩݙ͢Δ͔Ͳ͏͔ʁ 3BKFTXBSBO "
    FU
    BM
    .FUB-FBSOJOH
    XJUI
    *NQMJDJU
    (SBEJFOUT
    /FVS*14  )BO
    )
    FU
    BM
    3FMBUJPO
    /FUXPSLT
    GPS
    0CKFDU
    %FUFDUJPO
    $713
     4.
    .D,JOOFZ
    FU
    BM
    *OUFSOBUJPOBM
    FWBMVBUJPO
    PG
    BO
    "*
    TZTUFN
    GPS
    CSFBTU
    DBODFS
    TDSFFOJOH
    /BUVSF
    
    
     ⁢ ҩྍݱ৔΁ͷಋೖ ͜ͱ͹ͷ"*͸Ͳ͜·Ͱҩྍʹߩݙ͍ͯ͠Δ͔ ⁠ ҩྍσʔλͰͷݕূ ҩ༻ը૾΍ిࢠΧϧςΛՃ޻ͨ͠ެ։σʔλ΍ɼ ຊ෺ͷ୯ࢪઃʙଟࢪઃσʔλͰͷݚڀ ٕज़ྲྀೖʹ͸͕͔͔࣌ؒΔ
30. ⁞ "*جૅٕज़ͷൃల "*ͷ࢓૊Έʹର͢Δཧ࿦తɾجૅతͳݚڀ   ը૾ॲཧࣗવݴޠॲཧͷൃల "*ݚڀ༻ͷඇҩྍσʔλΛ࢖ͬͨݚڀ ⁡ ҩྍݱ৔Ͱͷݕূ ҩྍݱ৔ʹ࣮ࡍʹߩݙ͢Δ͔Ͳ͏͔ʁ 3BKFTXBSBO "
    FU
    BM
    .FUB-FBSOJOH
    XJUI
    *NQMJDJU
    (SBEJFOUT
    /FVS*14  )BO
    )
    FU
    BM
    3FMBUJPO
    /FUXPSLT
    GPS
    0CKFDU
    %FUFDUJPO
    $713
     4.
    .D,JOOFZ
    FU
    BM
    *OUFSOBUJPOBM
    FWBMVBUJPO
    PG
    BO
    "*
    TZTUFN
    GPS
    CSFBTU
    DBODFS
    TDSFFOJOH
    /BUVSF
    
    
     ⁢ ҩྍݱ৔΁ͷಋೖ ͜ͱ͹ͷ"*͸Ͳ͜·Ͱҩྍʹߩݙ͍ͯ͠Δ͔ ⁠ ҩྍσʔλͰͷݕূ ҩ༻ը૾΍ిࢠΧϧςΛՃ޻ͨ͠ެ։σʔλ΍ɼ ຊ෺ͷ୯ࢪઃʙଟࢪઃσʔλͰͷݚڀ ٕज़ྲྀೖʹ͸͕͔͔࣌ؒΔ
31. ⁞ "*جૅٕज़ͷൃల "*ͷ࢓૊Έʹର͢Δཧ࿦తɾجૅతͳݚڀ   ը૾ॲཧࣗવݴޠॲཧͷൃల "*ݚڀ༻ͷඇҩྍσʔλΛ࢖ͬͨݚڀ ⁡ ҩྍݱ৔Ͱͷݕূ ҩྍݱ৔ʹ࣮ࡍʹߩݙ͢Δ͔Ͳ͏͔ʁ 3BKFTXBSBO "
    FU
    BM
    .FUB-FBSOJOH
    XJUI
    *NQMJDJU
    (SBEJFOUT
    /FVS*14  )BO
    )
    FU
    BM
    3FMBUJPO
    /FUXPSLT
    GPS
    0CKFDU
    %FUFDUJPO
    $713
     4.
    .D,JOOFZ
    FU
    BM
    *OUFSOBUJPOBM
    FWBMVBUJPO
    PG
    BO
    "*
    TZTUFN
    GPS
    CSFBTU
    DBODFS
    TDSFFOJOH
    /BUVSF
    
    
     ⁢ ҩྍݱ৔΁ͷಋೖ ͜ͱ͹ͷ"*͸Ͳ͜·Ͱҩྍʹߩݙ͍ͯ͠Δ͔ ⁠ ҩྍσʔλͰͷݕূ ҩ༻ը૾΍ిࢠΧϧςΛՃ޻ͨ͠ެ։σʔλ΍ɼ ຊ෺ͷ୯ࢪઃʙଟࢪઃσʔλͰͷݚڀ ٕज़ྲྀೖʹ͸͕͔͔࣌ؒΔ
32. ⁞ "*جૅٕज़ͷൃల "*ͷ࢓૊Έʹର͢Δཧ࿦తɾجૅతͳݚڀ   ը૾ॲཧࣗવݴޠॲཧͷൃల "*ݚڀ༻ͷඇҩྍσʔλΛ࢖ͬͨݚڀ ⁡ ҩྍݱ৔Ͱͷݕূ ҩྍݱ৔ʹ࣮ࡍʹߩݙ͢Δ͔Ͳ͏͔ʁ 3BKFTXBSBO "
    FU
    BM
    .FUB-FBSOJOH
    XJUI
    *NQMJDJU
    (SBEJFOUT
    /FVS*14  )BO
    )
    FU
    BM
    3FMBUJPO
    /FUXPSLT
    GPS
    0CKFDU
    %FUFDUJPO
    $713
     4.
    .D,JOOFZ
    FU
    BM
    *OUFSOBUJPOBM
    FWBMVBUJPO
    PG
    BO
    "*
    TZTUFN
    GPS
    CSFBTU
    DBODFS
    TDSFFOJOH
    /BUVSF
    
    
     ⁢ ҩྍݱ৔΁ͷಋೖ ͜ͱ͹ͷ"*͸Ͳ͜·Ͱҩྍʹߩݙ͍ͯ͠Δ͔ ⁠ ҩྍσʔλͰͷݕূ ҩ༻ը૾΍ిࢠΧϧςΛՃ޻ͨ͠ެ։σʔλ΍ɼ ຊ෺ͷ୯ࢪઃʙଟࢪઃσʔλͰͷݚڀ ٕज़ྲྀೖʹ͸͕͔͔࣌ؒΔ
33. ⁞ "*جૅٕज़ͷൃల "*ͷ࢓૊Έʹର͢Δཧ࿦తɾجૅతͳݚڀ   ը૾ॲཧࣗવݴޠॲཧͷൃల "*ݚڀ༻ͷඇҩྍσʔλΛ࢖ͬͨݚڀ ⁡ ҩྍݱ৔Ͱͷݕূ ҩྍݱ৔ʹ࣮ࡍʹߩݙ͢Δ͔Ͳ͏͔ʁ 3BKFTXBSBO "
    FU
    BM
    .FUB-FBSOJOH
    XJUI
    *NQMJDJU
    (SBEJFOUT
    /FVS*14  )BO
    )
    FU
    BM
    3FMBUJPO
    /FUXPSLT
    GPS
    0CKFDU
    %FUFDUJPO
    $713
     4.
    .D,JOOFZ
    FU
    BM
    *OUFSOBUJPOBM
    FWBMVBUJPO
    PG
    BO
    "*
    TZTUFN
    GPS
    CSFBTU
    DBODFS
    TDSFFOJOH
    /BUVSF
    
    
     ⁢ ҩྍݱ৔΁ͷಋೖ ͜ͱ͹ͷ"*͸Ͳ͜·Ͱҩྍʹߩݙ͍ͯ͠Δ͔ ⁠ ҩྍσʔλͰͷݕূ ҩ༻ը૾΍ిࢠΧϧςΛՃ޻ͨ͠ެ։σʔλ΍ɼ ຊ෺ͷ୯ࢪઃʙଟࢪઃσʔλͰͷݚڀ ٕज़ྲྀೖʹ͸͕͔͔࣌ؒΔ
34. ⁞ "*جૅٕज़ͷൃల "*ͷ࢓૊Έʹର͢Δཧ࿦తɾجૅతͳݚڀ   ը૾ॲཧࣗવݴޠॲཧͷൃల "*ݚڀ༻ͷඇҩྍσʔλΛ࢖ͬͨݚڀ ⁡ ҩྍݱ৔Ͱͷݕূ ҩྍݱ৔ʹ࣮ࡍʹߩݙ͢Δ͔Ͳ͏͔ʁ 3BKFTXBSBO "
    FU
    BM
    .FUB-FBSOJOH
    XJUI
    *NQMJDJU
    (SBEJFOUT
    /FVS*14  )BO
    )
    FU
    BM
    3FMBUJPO
    /FUXPSLT
    GPS
    0CKFDU
    %FUFDUJPO
    $713
     4.
    .D,JOOFZ
    FU
    BM
    *OUFSOBUJPOBM
    FWBMVBUJPO
    PG
    BO
    "*
    TZTUFN
    GPS
    CSFBTU
    DBODFS
    TDSFFOJOH
    /BUVSF
    
    
     ⁢ ҩྍݱ৔΁ͷಋೖ ͜ͱ͹ͷ"*͸Ͳ͜·Ͱҩྍʹߩݙ͍ͯ͠Δ͔ ⁠ ҩྍσʔλͰͷݕূ ҩ༻ը૾΍ిࢠΧϧςΛՃ޻ͨ͠ެ։σʔλ΍ɼ ຊ෺ͷ୯ࢪઃʙଟࢪઃσʔλͰͷݚڀ ٕज़ྲྀೖʹ͸͕͔͔࣌ؒΔ
35. ⁞ "*جૅٕज़ͷൃల "*ͷ࢓૊Έʹର͢Δཧ࿦తɾجૅతͳݚڀ   ը૾ॲཧࣗવݴޠॲཧͷൃల "*ݚڀ༻ͷඇҩྍσʔλΛ࢖ͬͨݚڀ ⁡ ҩྍݱ৔Ͱͷݕূ ҩྍݱ৔ʹ࣮ࡍʹߩݙ͢Δ͔Ͳ͏͔ʁ 3BKFTXBSBO "
    FU
    BM
    .FUB-FBSOJOH
    XJUI
    *NQMJDJU
    (SBEJFOUT
    /FVS*14  )BO
    )
    FU
    BM
    3FMBUJPO
    /FUXPSLT
    GPS
    0CKFDU
    %FUFDUJPO
    $713
     4.
    .D,JOOFZ
    FU
    BM
    *OUFSOBUJPOBM
    FWBMVBUJPO
    PG
    BO
    "*
    TZTUFN
    GPS
    CSFBTU
    DBODFS
    TDSFFOJOH
    /BUVSF
    
    
     ⁢ ҩྍݱ৔΁ͷಋೖ ͜ͱ͹ͷ"*͸Ͳ͜·Ͱҩྍʹߩݙ͍ͯ͠Δ͔ ⁠ ҩྍσʔλͰͷݕূ ҩ༻ը૾΍ిࢠΧϧςΛՃ޻ͨ͠ެ։σʔλ΍ɼ ຊ෺ͷ୯ࢪઃʙଟࢪઃσʔλͰͷݚڀ ٕज़ྲྀೖʹ͸͕͔͔࣌ؒΔ ޻ֶܥ ݚڀऀ ҩֶܥ ݚڀऀ
36. ⁞ "*جૅٕज़ͷൃల "*ͷ࢓૊Έʹର͢Δཧ࿦తɾجૅతͳݚڀ   ը૾ॲཧࣗવݴޠॲཧͷൃల "*ݚڀ༻ͷඇҩྍσʔλΛ࢖ͬͨݚڀ ⁡ ҩྍݱ৔Ͱͷݕূ ҩྍݱ৔ʹ࣮ࡍʹߩݙ͢Δ͔Ͳ͏͔ʁ 3BKFTXBSBO "
    FU
    BM
    .FUB-FBSOJOH
    XJUI
    *NQMJDJU
    (SBEJFOUT
    /FVS*14  )BO
    )
    FU
    BM
    3FMBUJPO
    /FUXPSLT
    GPS
    0CKFDU
    %FUFDUJPO
    $713
     4.
    .D,JOOFZ
    FU
    BM
    *OUFSOBUJPOBM
    FWBMVBUJPO
    PG
    BO
    "*
    TZTUFN
    GPS
    CSFBTU
    DBODFS
    TDSFFOJOH
    /BUVSF
    
    
     ⁢ ҩྍݱ৔΁ͷಋೖ ͜ͱ͹ͷ"*͸Ͳ͜·Ͱҩྍʹߩݙ͍ͯ͠Δ͔ ⁠ ҩྍσʔλͰͷݕূ ҩ༻ը૾΍ిࢠΧϧςΛՃ޻ͨ͠ެ։σʔλ΍ɼ ຊ෺ͷ୯ࢪઃʙଟࢪઃσʔλͰͷݚڀ ٕज़ྲྀೖʹ͸͕͔͔࣌ؒΔ ·ͩϋʔυϧ͕ߴ͍ ͜ͷݚڀ͸׆ൃ
37. ͜ͱ͹ͷ"*͸Ͳ͜·Ͱҩྍʹߩݙ͍ͯ͠Δ͔ ྫɿಡӨϨϙʔτͷࣗಈੜ੒ "*ݚڀɿΩϟϓγϣϯੜ੒λεΫ ɾຕͷը૾͔Β୹จΛੜ੒ ɾݫີ͞͸͞΄Ͳ໰ΘΕͳ͍ ์ࣹઢՊҩϨϕϧͷಡӨϨϙʔτ࡞੒ ɾຕʙଟ਺ͷը૾͔Β ɾ೥ྸ
    ੑผ
    ྟচ৘ใ
    աڈը૾΋Έͯ௕จΛੜ੒ ɾ಺༰ͷݫີ͕͞ٻΊΒΕΔ ϋʔυϧ͕ߴ͍ :
    1BO
    FU
    BM
    .FE8SJUFS
    ,OPXMFEHF"XBSF
    .FEJDBM
    5FYU
    (FOFSBUJPO
    *O
    QSPDFFEJOHT
    PG
    UIF
    UI
    *OUFSOBUJPOBM
    $POGFSFODF
    PO
    $PNQVUBUJPOBM
    -JOHVJTUJDT
    $0-*/( 
    
    
38. :
    1BO
    FU
    BM
    .FE8SJUFS
    ,OPXMFEHF"XBSF
    .FEJDBM
    5FYU
    (FOFSBUJPO
    *O
    QSPDFFEJOHT
    PG
    UIF
    UI
    *OUFSOBUJPOBM
    $POGFSFODF
    PO
    $PNQVUBUJPOBM
    -JOHVJTUJDT
    $0-*/( 
    
    ͜ͱ͹ͷ"*͸Ͳ͜·Ͱҩྍʹߩݙ͍ͯ͠Δ͔ ྫɿಡӨϨϙʔτͷࣗಈੜ੒ "*ݚڀɿΩϟϓγϣϯੜ੒λεΫ ɾຕͷը૾͔Β୹จΛੜ੒ ɾݫີ͞͸͞΄Ͳ໰ΘΕͳ͍ ์ࣹઢՊҩϨϕϧͷಡӨϨϙʔτ࡞੒ ɾຕʙଟ਺ͷը૾͔Β ɾ೥ྸ
    ੑผ
    ྟচ৘ใ
    աڈը૾΋Έͯ௕จΛੜ੒ ɾ಺༰ͷݫີ͕͞ٻΊΒΕΔ ϋʔυϧ͕ߴ͍ ϋʔυϧΛएׯԼ͛Δ ҩྍσʔλͰͷݕূ ɾຕʙଟ਺ͷը૾͔Β ɾ೥ྸ
    ੑผ
    ྟচ৘ใ
    աڈը૾΋Έͯ௕จΛੜ੒ ɾ಺༰ͷݫີ͞͸͋Δఔ౓ଥڠ͢Δ
39. 8V
    4
    FU
    BM
    %FFQ
    MFBSOJOH
    JO
    DMJOJDBM
    OBUVSBM
    MBOHVBHF
    QSPDFTTJOH
    B
    NFUIPEJDBM
    SFWJFX
    +
    "N
    .FE
    *OGPSN
    "TTPD
      
    
     ͜ͱ͹ͷ"*͸Ͳ͜·Ͱҩྍʹߩݙ͍ͯ͠Δ͔ ը૾"*ͱ͘Β΂ͯ਺೥஗Ε͍ͯΔ͕ɼ ݚڀ͸ٸ଎ʹ੝Γ্͕͖͍ͬͯͯΔ ҩྍจॻʹਂ૚ֶशΛద༻ͨ͠࿦จͷຊ਺   
    +BO"QS 
40. Ͱ͸ɼͲͷΑ͏ͳݚڀ͕͞Ε͍ͯΔ͔ʁ ͜ͱ͹ͷ"*͸Ͳ͜·Ͱҩྍʹߩݙ͍ͯ͠Δ͔
41. ҩྍจॻ ΧϧςͳͲ ࿦จ ױऀςΩετ ҩྍݴޠॲཧ͕ओʹѻ͏σʔλͭ ͜ͱ͹ͷ"*͸Ͳ͜·Ͱҩྍʹߩݙ͍ͯ͠Δ͔
42. ҩྍจॻ ΧϧςͳͲ ࿦จ ױऀςΩετ ҩྍݴޠॲཧ͕ओʹѻ͏σʔλͭ ͜ͱ͹ͷ"*͸Ͳ͜·Ͱҩྍʹߩݙ͍ͯ͠Δ͔
43. ࣗಈείΞϦϯά ɾ৺๪ࡉಈױऀͷΧϧς͔Β೴ߎ࠹ϦεΫ $)" %4 7"4D
    ΍ ग़݂ϦεΫ )"4#-&%
    Λࣗಈ൑ఆ ɾ$)" %4 7"4Dʾɼ)"4#-&%ʾ
    ʹର͢Δ ཅੑతத཰ʙ 4IJSMFZ
    7
    8BOH
    FU
    BM
    6TF
    PG
    FMFDUSPOJD
    IFBMUIDBSF
    SFDPSET
    UP
    JEFOUJGZ
    DPNQMFY
    QBUJFOUT
    XJUI
    BUSJBM
    GJCSJMMBUJPO
    GPS
    UBSHFUFE JOUFSWFOUJPO
    +PVSOBM
    PG
    UIF
    "NFSJDBO
    .FEJDBM
    *OGPSNBUJDT
    "TTPDJBUJPO
    7PMVNF
    
    *TTVF
    
    .BSDI
    
    1BHFT
    r ͜ͱ͹ͷ"*͸Ͳ͜·Ͱҩྍʹߩݙ͍ͯ͠Δ͔ Partners HealthCare System Research Patient Data Registry (RPDR) 480 patient charts CHA2 DS2 -VASc score= ? HAS-BLED score = ?
44. ֎དྷΧϧςࣗಈ࡞੒ r $MVTUFSTFOU ɾ֎དྷԻ੠ͷจࣈى͜͠Λ40"1ܗࣜͷΧϧςʹࣗಈม׵ ɾӳޠެ։σʔληοτ ".*
    .FFUJOH
    $PSQVT
    Λར༻ ,VOEBO
    ,
    FU
    BM
    (FOFSBUJOH
    40"1
    /PUFT
    GSPN
    %PDUPS1BUJFOU
    $POWFSTBUJPOT
    6TJOH
    .PEVMBS
    4VNNBSJ[BUJPO
    5FDIOJRVFT
    "$-
     +
    $BSMFUUB
    FU
    BM
    6OMFBTIJOH
    UIF
    LJMMFS
    DPSQVT
    FYQFSJFODFT
    JO
    DSFBUJOH
    UIF
    NVMUJFWFSZUIJOH
    ".*
    .FFUJOH
    $PSQVT
    -3&$
     ͜ͱ͹ͷ"*͸Ͳ͜·Ͱҩྍʹߩݙ͍ͯ͠Δ͔
45. ྟচࢼݧͷద֨ੑͷࣗಈ൑ఆ ɾ౶೘පױऀ໊ʹ͍ͭͯΧϧςΛ΋ͱʹݸͷج४Λ൑ఆ͠ ྟচࢼݧͷ૊ΈೖΕج४ΛΈ͔ͨ͢Ͳ͏͔ࣗಈ൑ఆ '
    TDPSF
    Λୡ੒ :
    9JPOH FU
    BM
    $PIPSU
    TFMFDUJPO
    GPS
    DMJOJDBM
    USJBMT
    VTJOH
    IJFSBSDIJDBM
    OFVSBM
    OFUXPSL
    +PVSOBM
    PG
    UIF
    "NFSJDBO
    .FEJDBM
    *OGPSNBUJDT
    "TTPDJBUJPO
     
    
    r ͜ͱ͹ͷ"*͸Ͳ͜·Ͱҩྍʹߩݙ͍ͯ͠Δ͔ Met? Non-met?
46. ҩྍจॻ ΧϧςͳͲ ࿦จ ױऀςΩετ ҩྍݴޠॲཧ͕ओʹѻ͏σʔλͭ ͜ͱ͹ͷ"*͸Ͳ͜·Ͱҩྍʹߩݙ͍ͯ͠Δ͔
47. ѱੑजᙾͷ QSFDJTJPO
    NFEJDJOF
    ࢧԉ ɾ͍ΘΏΔ ΦʔμʔϝΠυҩྍ
    ΁ͷԠ༻Λ૝ఆ ɾ৚݅ʹద࣏ͨ͠ྍ๏Λ;͘Ήจݙ΍ྟচࢼݧΛࣗಈݕࡧ ,
    3PCFSUT
    FU
    BM
    0WFSWJFX
    PG
    UIF
    53&$
    
    1SFDJTJPO
    .FEJDJOF
    5SBDL
    *O
    QSPDFFEJOHT
    PG
    UIF
    5XFOUZ&JHIUI
    5FYU
    3FUSJFWBM
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