data described in this article are available at http:// europepmc.org/ftp/oa/AccNoAnalysisData/. N The Whatizit ANA pipeline for ENA, UniProt and PDB accession numbers is integrated into the ePMC infrastructure and all the gathered accession numbers are available via the ePMC web site and web services (http://europepmc.org/ WebServices). N The extensions and improvements to the Whatizit ANA pipeline will be applied to the ePMC core program of named entity recognition and will be available via the web site and web services. N Tagged versions of the OA article set will be made available on an ongoing basis from the FTP site in the future. Acknowledgments We would like to thank the Rebholz research group at the EBI (2003-2012) for developing the Whatizit service, the EBI Literature Services Group for the development of many of the core data services used in this study, Andrew Caines for help producing the figures and Alex Bateman for critical reading of the manuscript. Author Contributions Conceived and designed the experiments: S ¸K JK JRM. Performed the experiments: S ¸K JK. Analyzed the data: S ¸K JK JRM. Wrote the paper: S ¸K JK JRM. References 1. Kahn P, Hazledine D (1988) NAR’s new requirement for data submission to the EMBL data library: information for authors. Nucleic Acids Res 16(10): I–IV. 2. Science as an Open Enterprise (2012) The Royal Society. Available: http:// royalsociety.org/policy/projects/science-public-enterprise/report/. Accessed 2013 Apr 8. 3. Rebholz-Schuhmann D, Arregui M, Gaudan S, Kirsch H, Yepes AJ (2007) Text processing through Web services: calling Whatizit. Bioinformatics 24(2):296– 298. 4. McEntyre JR, Ananiadou S, Andrews S, Black WJ, Boulderstone R, et al. (2011) UKPMC: a full text article resource for the life sciences. Nucleic Acids Res 39:d58–65. 5. Ne ´ve ´ol A, Wilbur WJ, Lu Z (2011) Extraction of data deposition statements from the literature: a method for automatically tracking research results. Bioinfor- matics 27(23):3306–3312. 6. Ne ´ve ´ol A, Wilbur WJ, Lu Z (2012) Improving links between literature and biological data with text mining: a case study with GEO, PDB and MEDLINE. Database (Oxford) 2012: bas026. 7. Fink JL, Kushch S, Williams PR, Bourne PE (2008) BioLit: integrating biological literature with databases. Nucleic Acids Res 36(Web Server Issue):W385–9. 8. Haeussler M, Gerner M, Bergman CM (2011) Annotating genes and genomes with DNA sequences extracted from biomedical articles. Bioinformatics 27(7):980–6. 9. Finn RD, Mistry J, Tate J, Coggill P, Heger A, et al. (2010) The Pfam protein families database. Nucleic Acids Res Database Issue 38:D211–222. 10. Parkinson H, Sarkans U, Shojatalab M, Abeygunawardena N, Contrino S, et al. (2005) ArrayExpress – a public repository for microarray gene expression data at the EBI. Nucleic Acids Res (2005) 33 (Suppl 1): D553–D555. 11. Mulder NJ, Apweiler R, Attwood TK, Bairoch A, Bateman A, et al. (2002) InterPro: an integrated documentation resource for protein families, domains and functional sites. Brief Bioinform (3):225–35. http://dx.doi.org/10.1371/journal.pone.0063184