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The 3rd Open Science Award

The 3rd Open Science Award

Tazro Inutano Ohta

March 17, 2016
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  1. Best Database ChIP-Atlas! AOE (All Of gene Expression)! RDF Portal

    for NBDC! RefEx! DNApod! BRCϚ΢εϦιʔεදݱܕϝλσʔλ! BRCࡉ๔Ϧιʔεදݱܕϝλσʔλ! JCMඍੜ෺Ϧιʔεϝλσʔλ! NBRPϝμΧදݱܕϝλσʔλ! Integrative Japanese Genome Variation Database! ཧݚϝλσʔλϕʔε
  2. Best Software meshr! mudi - mutation discovery! ΫϦοΫͪΌΜ! CRISPRdirect! smbt!

    Centroidfold! FuncTree! Gendoo! UMATracker! Cnocglas MolBrowser! Bayes Linux! GhostX! MEGADOCK
  3. Best Website/Article RͰԘج഑ྻղੳ/RͰϚΠΫϩΞϨΠσʔλղੳ! ύοΫϚϯͷ௅ઓ! ฏ੒27೥౓NGSϋϯζΦϯߨशձ - ChIP-Seqղੳجૅ! ʮ΍ʔ͍͓લͷ෕ͪΌΜόΠΦΠϯϑΥʔʂʯ! ੜ໋ՊֶݚڀΛߟ͑ΔΨνٞ࿦ˏୈ36ճ೔ຊ෼ࢠੜ෺ֶձ! ͳͥόΠΦΠϯϑΥϚςΟΫεͷղੳ͸λμͰ͸ͳ͍ͷ͔!

    NGSσʔλղੳසग़୯ޠू! NGS͸೉͍͠ (Ծ)! όΠΦΠϯϑΥͰ࣮ݧϊʔτΛऔΖ͏! biopapyrus! CloudBioLinuxΛ༻͍ͯϩʔΧϧαʔόʹNGSղੳ؀ڥΛߏங͢Δ! bio෼໺޲͚ͷDockerίϯςφΛͭ͘Δ on MacOSX
  4. -JDFOTFEVOEFSB$$#:˜খ໺ߒխ %#$-4 3FG&Yͷಛ௕ ๏ਖ਼ৗ૊৫ɾଁثͷҨ఻ࢠൃݱঢ়گΛͻͱ໨Ͱ ๏ ͭͷҟͳΔ࣮ݧख๏ʹΑͬͯಘΒΕͨछྨͷਖ਼ৗ૊৫ɾଁث
 ʹ͓͚ΔҨ఻ࢠൃݱσʔλΛฒྻʹදݱ ๏ ࿦จͰݟ͔͚ͨೃછΈͷͳ͍Ҩ఻ࢠ͕ͲͷଁثͰൃݱ͍ͯ͠Δͷ͔
 ࣮ࡍͷଌఆσʔλ͔Βݚڀऀࣗ਎ͷ໨Ͱ؆୯ʹ֬ೝ


    ๏ௐ΂͍ͨҨ఻ࢠΛΑΓ୳͠΍͘͢ΑΓ෼͔Γ΍͘͢ ๏ ň૊৫ಛҟతҨ఻ࢠʼnΛଌఆσʔλ͔Βಠࣗʹࢉग़͠ɺ૊৫͝ͱʹ
 ҰཡՄೳ ๏ "EWBODFETFBSDI΍ߜΓࠐΈݕࡧΛ࢖ͬͯෳࡶͳݕࡧ৚݅΋
 ࢦఆՄೳͰɺ໨తͱ͢ΔσʔλΛ؆୯ʹݕࡧ ๏௚ײతͳՄࢹԽͰ৽ͨͳ஌ࣝൃݟɾԾઆߏஙΛ ๏ ૊৫ؒͷൺֱͱଌఆख๏ؒͷൺֱΛཱ྆ͤͨ͞૬ରൃݱྔͷ
 όʔνϟʔτ΍ਓମ%ϞσϧʹൃݱྔΛ൓өͤͨ͞ώʔτϚοϓ ๏ ೚ҙͰબΜͩ࠷େͭͷҨ఻ࢠͷൃݱσʔλΛฒྻʹൺֱͰ͖Δ
 Ϧετػೳ
 ๏࠶ར༻ՄೳͰ༗༻ͳύϒϦοΫσʔλͷ׆༻ྫ ๏ ੜ໋Պֶσʔλͷڞ༗͓Αͼ࠶ར༻ͷ׆༻ྫͷͻͱͭͰ͋Γɺ
 σʔλۦಈܕݚڀͷͨΊͷπʔϧͱͯͩ͠ΕͰ΋ࣗ༝ʹར༻Մೳ
  5. -JDFOTFEVOEFSB$$#:˜খ໺ߒխ %#$-4 '"/50.$"(&σʔλ ๏ ώτछ ๏ Ϛ΢εछ w ࡉ๔ג w

    ॳ୅ഓཆࡉ๔ w ੒ମ૊৫ w ଻ࣇ૊৫ ๏ ଞͷσʔλʹઌۦ͚ͯ
 3%'Խ w ϏϡʔΞ࡞੒த w ελϯβԽ΁
  6. -JDFOTFEVOEFSB$$#:˜খ໺ߒխ %#$-4 5IF3FG&YBOBMZTJT ๏ ࣮ݧͰݟग़ͨ͠ඪతɾ ީิҨ఻ࢠͷൃݱྔ͕ ਖ਼ৗ૊৫ͰۃΊͯ
 ௿͍͜ͱΛ֬ೝ ๏ ͜ΕΒͷҨ఻ࢠΛ


    ࣏ྍඪతͱͨ͠৔߹ʹ ਖ਼ৗ૊৫΁ͷӨڹ͕
 খ͍͞Ŋͱ༧ଌͰ͖ͨ
 ๏ 3FG&YσʔλΛࣗ෼Ͱ
 Ճ޻ͯ͠ŊਤΛ࡞੒
  7. ϥΠϑαΠΤϯε౷߹σʔλϕʔεηϯλʔ %#$-4  ɹ ɹ ɹ ɹ ɹ ɹ 

    ಺ ౻ ༤ थ 
 ɹ ɹ ɹ ɹ ɹ   !NFTP@DBDBTF ɹήϊϜฤूͷͨΊͷ
 ΨΠυ3/"ઃܭπʔϧ 5XFFU0, CRISPRdirect
  8. $3*413EJSFDU chr1:562688-562700 chr1:793957-793969 chr1:957810-957824 chr1:1085660-1085674 chr1:1373831-1373844 chr1:1482921-1482934 chr1:1526112-1526124 562688 793957

    957810 1085660 1373831 1482921 1526112 Mismatches G G C A C G Matches are highlighted with blue background. and indels are marked in red. GAAGAAAGGGGAGTGGGCACGAAATACTAC AACGAAGTCCCTCTGTCTGTGTGTGCCTAT AGGCTGCTGGCCTGGAAGGTAGTCACGTGG ATGAGATTGGAAAGTAGTAATAAGCCATGT TCAACTCCAGCCTCATGCGGATCACCCTGC TGGAGTTCTGTGTGGAAGGTGCGTGGTGGG CAGACACACAGGCCCACCCAGGTGGGTCCC GCCTTGCCTGCCCTGTGTTCCTTCCTGGAG GGGGATGGGAAGAAAGTGGCCCAGGCACCC AAGATCCTGATAGCTTTAACCCAGCGCAGA CTAGACCTGCAAGCCCCACCAGAGGCTGTG ACCAAAGGGACCACAGACCAAGCCATGAGC TACTTGGGAGGTCGAGGCAGGAGAATGGCG CGGAGCTTGCAGTGAGCAGAGATCGCACCA AGAACCTGCA- -G- -GG AGAACC- -GCAGGA- -G GAACCTG AGGAGG AG ACCTGCAGGA G AG A- -CTGCAGGAGG AG ACCTG- -AGGAGG AGAACCTGC- -- -GAGG
  9. 2011 2012 2013 2014 2015 2016 2010 2017 *#.8BUTPO͕+FPQBSEZͰ༏উ ୈճΦʔϓϯόΠΦݚڀձ

    ʮ8BUTPOΫΠζ൪૊΁ͷ௅ઓɺΛ௒͑Ζʂͦͷ໊͸$SJDLʯࠤ౻ݡೋ ୈճΦʔϓϯόΠΦݚڀձ4*(.#* ςʔϚɿόΠΦ൛4JSJʢԾশɿΫϦοΫͪΌΜʣ։ൃʹ͍ͭͯٞ࿦ ʮʬΫϦοΫͪΌΜʭΛ૑ΔͨΊʹ͸Կ͕ඞཁ͔(MBOHVBHF1SPKFDUͷΞϓϩʔνʯߥ઒࿨੖ #JP)BDLBUIPO ʮ(&/*&ʯ(MBOHVBHF1SPKFDU “Finally, the project that generated the most “buzz” among the participants in BioHackathon 2012 was Genie - a “Siri for Biologists”. “ J. Biomed. Semantics. (2014) /#%$%#$-4ڞಉݚڀܭը ʮNCBD/DBCLS ࣭ٙԠ౴γεςϜʯยࢁढ़໌ ࣗવݴޠͰɺ୯ޠͰ͸ͳ͘ɺจΛݕࡧ͢ΔγεςϜ
  10. ࣭໰ ߏจղੳ ࣭໰Ͱ͸ͳ͘ձ࿩ʁ ΫΤϦ֦ு ఆܕ࣭໰ɿήϊϜղੳ༻ ԣஅݕࡧɿϖʔδ ׬શจநग़ Heuristic Scoring Filtering

    τοϓ̑ީิ ׬શจͰ۩ମతͳ࣭໰͕ඞཁ Problem: ࣗવʹձ࿩ɾର࿩Λͨ͘͠ͳΔ ϢʔβΠϯλϑΣΠε Goal: Ϧιʔε͕ͳ͍͔Β͕͔͔࣌ؒΔ Problem: ଴ͭࣄ͕ۤʹͳΒͳ͍ ϢʔβΠϯλϑΣΠε Goal: ਫ਼౓͸ͦ͜·ͰݟࠐΊͳ͍ Problem: ؒҧͬͯ΋ڐͪ͠Ό͏ ϢʔβΠϯλϑΣΠε Goal:
  11. RͰԘج഑ྻղੳ/! RͰϚΠΫϩΞϨΠσʔλղੳ ݴΘͣͱ஌Ε໊ͨ෺ςΩετɻ͜ΕΛݩʹߨशձ͕։࠵͞ΕͨΓɺຊ ͕ग़൛͞ΕͨΓ͍ͯ͠·͢ɻܧଓͯ͠Ξοϓσʔτɺख๏ͷൺֱ΍ච ऀͷίϝϯτͳͲඇৗʹ༗༻Ͱ͢ɻ! ! ։ൃऀ (౦ژେֶ ໳ా޾ೋ͞Μ) ͔Βͷίϝϯτ:!

    ʮࣗ෼Ͱࣗ෼͚ͩʹ౤ථ͍ͯ͠Ε͹୯ಠҰҐͩͬͨͷͰ͢Ͷw ݴ͍ͨ ͍์୊΍Γ͍ͨ์୊ͷ໳ాʹ΋౤ථͯͩ͘͠͞Δํ͕Ұఆͷׂ߹Ͱ͍ Βͬ͠ΌΔͷ͸͋Γ͕͍ͨ͜ͱͰ͢ɻ͜Ε͔Β΋ϙδγϣϯ͕ଓ͔͘ ͗ΓɺͰ͖Δ͚ͩΞοϓσʔτΛ͢ΔॴଘͰ͢ʯ
  12. •ྑ͍اըͰ͢! •ΫϦοΫͪΌΜ ͔ΘE! •͍ͭ΋͋Γ͕ͱ͏͍͟͝·͢ (^^)! •೰·͍͠ɻɻͱͯ΋೰·͍͠ɻɻ! •஌Βͳ͍αʔϏεΛ஌Δ͜ͱ͕Ͱ͖ͯษڧʹͳΓ·͢! •ީิϦετΛݟΔ͜ͱͰຖ೥ษڧ͍͖͍ͤͯͨͩͯ͞·͢! •ຖ౓ɺ͓͔ͭΕ͞·Ͱ͢! •ࠓ೥͸Φʔϓϯιʔεʹߩݙ͢Δ೥ʹ͍ͨ͠ͱߟ͍͑ͯ·͢!

    •օ༷ͷ͓͔͛Ͱ೔ʑͷղੳ͕ਐΊΒΕ·͢ɻ͋Γ͕ͱ͏͍͟͝·͢ɻ! •͍ͭ΋͓ੈ࿩ʹͳ͍ͬͯΔ΋ͷͩͬͨΓɺॳΊ·ͯ͠ͷ΋ͷͩͬͨΓɺࠓճ΋ 1ͭ1͕ͭษڧʹͳΓ·ͨ͠ɻ! •͜ͷاը͸ࠓޙ΋ͥͻܧଓͯ͠Լ͍͞ɻڱٛͷόΠΦΠϯϑΥϚςΟΫεͰ͸ ͳ͘ɺԠ༻όΠΦΠϯϑΥϚςΟΫεʹؔ͢Δ೔ຊͷίϛϡχςΟʔͷ౒ྗͷ ྺ࢙͕ࠁ·Ε͍ͯΔͱࢥ͍·͢ɻ